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Cell Line Identification Technical Information
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Please click on the following links for more information on;
A number of significant publication have been shown to demonstrate that cell line contamination or mis-identification is a common phenomenon with those utilising cell lines for their research. This is of great concern to many in the research community as results obtained by using contaminated or mis-identified cell lines can be invalidated and misleading - wasting significant human and material resources. A number of journals are now trying to address the issue of cell line authentication in their Instructions for Authors. We expect the number of journals exercising similar authentication requirements to grow!
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Cancer Research
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From the 1st July 2009,
“Authors are required to address the following from cell lines described in their research:
a) from where and when the cell lines were obtained;
b) whether the cell lines have been tested and authenticated;
c) the method by which the cells were tested;
d) how and when the cells were last tested.
Cells obtained from a cell bank and passaged for less than 6 months do not require reauthentication.”
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Clinical Cancer Research
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Cancer Epidemiology, Biomarkers & Prevention
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Cancer Prevention Research
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Molecular Cancer Research
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Molecular Cancer Therapeutics
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Cancer Reviews Online
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Cancer Prevention Journals Portal (CPJP)
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International Journal of Cancer
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From the 1st January 2010,
“Manuscripts dealing with established cell lines have to provide authentication of cells by DNA profiling using short tandem repeats (STR)”
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References:
Clinical Cancer Research (2009) 15(13), p4251
International Journal of Cancer (2010) 126,1
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