Date added: 13/02/2014 Top Story: Prostate Cancer Biomarkers


Cell-based Research


Prostate Cancer Biomarkers


Adelaide researchers have used a panel of non-malignant control (RWPE-1, PNT1a and PNT2) and prostate cancer cell lines (22RV1, CaHPV10, DU-145 and LNCaP clone FCG) to evaluate a number of existing prostate cancer biomarkers, together with candidate endosomal and lysosomal proteins. Their findings were published in an article, Prostate Cell Lines as Models for Biomarker Discovery: Performance of Current Markers and the Search for New Biomarkers, in the 16 January 2014 issue of The Prostate. The cell lines PNT1a, PNT2, 22RV1 and LNCap clone FGC were obtained from the European Collection of Cell Cultures via CellBank Australia.


Good Cell Culture Practice


The Case for Standards in Life Science Research: Misidentification of Cell Lines


Members of the International Cell Line Authentication Committee (ICLAC) have summarised how the introduction of a single consensus standard on human cell line authentication in late 2011 has since transformed scientific attitudes and practices. Their Point of View article was published in the 1 February 2014 issue of Genetic Engineering and Biotechnology News (GEN) Magazine. The misidentification of human cell lines is one of the examples highlighted in the Global Biological Standards Institute (GBSI) report, “The Case for Standards in Life Science Research: Seizing Opportunities at a Time of Critical Need”, as released in December 2013.


Webinar on Animal Cell Line Authentication


The ATCC will present a webinar on the current technologies used to authenticate and characterize animal cell lines at 10am US and Canada EST on 27 February 2014 (this being 2am on 28 February 2014 here in Sydney, Australia). The webinar should be available on demand soon thereafter.