Description: Established from pleural effusion of 53 year old female with chronic myelogenous leukaemia in terminal blast crisis. Population highly undifferentiated and of the granulocytic series. Can be used as a highly sensitive target for the in vitro natural killer assay. Recent studies have shown the K562 blasts are multipotential, hematopoietic malignant cells that spontaneously differentiate into recognisable progenitors of the erythrocyte, granulocyte and monocytic series.

Also Known As:

Species: Human

Tissue: blood

Growth Properties: Suspension

Morphology: Lymphoblast

Growth Medium: RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Subculturing Procedure: Maintain cultures between 100,000 to 1,0,000 cells/ml; 5% CO2; 37°C.

Release Conditions: No

Depositor:

Originator: No

References: In J Cancer 1979;23:143; Leukaemia Res 1979;3:363; Proc. Soc. Exp. Biol. Med. 166:546-550, 1981

Hyperlink to ECACC Cell Line Data Sheet: 89121407