KG-1
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Description
Description: Derived from the bone marrow aspirate of a 59 year old male Caucasian with erythroleukemia that became acute myelogenous leukaemia. The cells form colonies in soft-agar in the presence of colony stimulating factor (CSF). KG-1 cells resemble acute myelogenous leukaemia showing considerable pleomorphism with a predominance of myeloblasts and promyelocytes. A small percentage of the cells are mature granulocytes with the occasional presence of macrophages and eosinophils. They do not express surface Ig or EBV antigens and lack specific markers for lymphocytic cells.
Also Known As:
Species: Human
Tissue: bone marrow
Growth Properties: Suspension
Morphology: Myeloblast-like
Growth Medium: IDMEM + 2mM Glutamine + 20% Foetal Bovine Serum (FBS).
Subculturing Procedure: Maintain cultures between 3-9×100000 cells/ml; 5% CO2; 37°C.
Release Conditions: No
Depositor:
Originator: No
References: Science 1978;200:1153; Blood 1980;56:344
Hyperlink to ECACC Cell Line Data Sheet: 86111306
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